In this paper, a microcantilever fiber optical biosensor based on Fabry-Pérot interferometric (FPI) was invented and used for antibiotic sensitivity testing (AST). This biosensor combines a cantilever and the single mode fiber (SMF) to form an FPI. After bacteria attach to the cantilever, their movement causes cantilever vibration, which can be obtained by measuring the change in dip wavelength of the interference spectrum. We used this biosensor to detected Escherichia coli, indicating the vibration amplitude of the cantilever increases with the increase of the number of bacteria fixed on the cantilever. Obtained the minimum inhibitory and bactericidal concentration against E. coli within 30 minutes, validating the rapid AST ability of this biosensor. The microcantilever fiber optical biosensor developed in this paper provides a novel technology for AST.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.