Computed laminography has become a popular tool to achieve high spatial resolution in three-dimensional imaging of flat, laterally extended objects. This study explores the synergy of synchrotron full-field micro-computed and scanning x-ray fluorescence laminography imaging, along with efficient data analysis software, to enhance x-ray imaging capabilities at beamlines 2-BM and 2-ID-E of the Advanced Photon Source at Argonne National Laboratory. We discuss the advantages of laminography imaging and demonstrate examples of laminography data acquisition and reconstruction for a flat mouse bone section measured at both beamlines. Reconstructed data provided structural information from the full-field micro-computed laminography measurements and elemental distribution from the fluorescence laminography measurements. Dragonfly ORS software was used to produce high-quality interactive volume and multichannel visualizations, facilitating the analysis of the 3D reconstructed data. The proposed integration of these two modalities for efficient structural and elemental analyses of samples holds the potential for substantial advancements in imaging technology.
Among different techniques based on x-ray nanoimaging, ptychography has become a popular tool to study specimens at nanometer-scale resolution without the need of using high-resolution optics that requires very stringent manufacturing processes. This high-resolution imaging method is compatible with other imaging modalities acquired in scanning microscopy. At the Advance Photon Source (APS), we have developed two fluorescence microscopes for simultaneous ptychography and fluorescence imaging which together provide a powerful technique to study samples in biology, environmental science, and materials science. Combined with different tilted sample projections, such correlative methods can yield high-resolution 3D structural and chemical images. More recent work has been focused on the development of a fast ptychography instrument called the Velociprobe which is built to take advantage of the over 100 times higher coherent flux provided by the coming APS upgrade source. The Velociprobe uses high-bandwidth accurate interferometry and advanced motion controls with fast continuous scanning schemes which are optimized for large-scale samples and 3D high-resolution imaging. This instrument has been demonstrated to obtain sub-10 nm resolution with different high-photon-efficient scanning schemes using fast data acquisition rate up to 3 kHz (currently limited by detector's full continuous frame rate). A ptychographic imaging rate of 100 _m2/second with a sub-20 nm spatial resolution was shown in this paper.
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