A new approach for optical system with liquid lenses is proposed in this paper. The method integrates genetic algorithm and simulated annealing algorithm to evaluate not only the current configurations of liquid lenses but also the optimization trend of the optical system. It makes a closer link between the liquid lenses configurations and the entire optical system, which is different from other algorithms and leads to a better performance in the optical system with liquid lenses. The result presents about 17% improvements compared to the same optical system optimized by conventional algorithms, from the values of the modulation transform function.
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