Dr. Laurence P. Clarke Profile

Dr. Laurence P. Clarke

DECEASED at National Cancer Institute

SPIE Involvement:

Author

Publications (27)

SPIE Journal Paper | 25 June 2015 Open Access

Open Access

Special Section Guest Editorial: LUNGx Challenge for computerized lung nodule classification: reflections and lessons learned

Samuel Armato, Lubomir Hadjiiski, Georgia Tourassi, Karen Drukker, Maryellen Giger, Feng Li, George Redmond, Keyvan Farahani, Justin S. Kirby, Laurence Clarke

JMI, Vol. 2, Issue 02, 020103, (June 2015) https://doi.org/10.1117/12.10.1117/1.JMI.2.2.020103

KEYWORDS: Medical imaging, Lung, Cancer, Calibration, Computed tomography, Oncology, Lung cancer, Databases, Algorithm development, Radiology

Proceedings Article | 30 March 2007 Paper

Paper

The Lung Image Database Consortium (LIDC): a quality assurance model for the collection of expert-defined truth in lung-nodule-based image analysis studies

Samuel Armato, Rachael Roberts, Geoffrey McLennan, Michael McNitt-Gray, David Yankelevitz, Ella Kazerooni, Edwin van Beek, Heber MacMahon, Denise Aberle, Charles Meyer, Anthony Reeves, Claudia Henschke, Eric Hoffman, Barbara Croft, Laurence Clarke

Proceedings Volume 6514, 651429 (2007) https://doi.org/10.1117/12.713227

KEYWORDS: Lung, Computed tomography, Databases, Computer aided diagnosis and therapy, Image quality, Solid modeling, Systems modeling, Image processing, Medical imaging, CAD systems

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Proceedings Article | 29 March 2007 Paper

Paper

The Lung Image Database Consortium (LIDC): pulmonary nodule measurements, the variation, and the difference between different size metrics

Anthony Reeves, Alberto Biancardi, Tatiyana Apanasovich, Charles Meyer, Heber MacMahon, Edwin van Beek, Ella Kazerooni, David Yankelevitz, Michael McNitt-Gray, Geoffrey McLennan, Samuel Armato, Denise Aberle, Claudia Henschke, Eric Hoffman, Barbara Croft, Laurence Clarke

Proceedings Volume 6514, 65140J (2007) https://doi.org/10.1117/12.713672

KEYWORDS: Databases, Lung, Computed tomography, Computer aided diagnosis and therapy, 3D image processing, Solids, Cancer, Lung cancer, Computing systems, Image processing

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Proceedings Article | 29 March 2007 Paper

Paper

The Lung Image Database Consortium (LIDC) data collection process for nodule detection and annotation

M. McNitt-Gray, S. Armato, C. Meyer, A. Reeves, G. McLennan, R. Pais, J. Freymann, M. Brown, R. Engelmann, P. Bland, G. Laderach, C. Piker, J. Guo, D. Qing, D. Yankelevitz, D. Aberle, E. van Beek, H. MacMahon, E. Kazerooni, B. Croft, L. Clarke

Proceedings Volume 6514, 65140K (2007) https://doi.org/10.1117/12.713754

KEYWORDS: Data processing, Image processing, Databases, Lung, Medical imaging, Computed tomography, Telecommunications, Data communications, Computer aided diagnosis and therapy, Medical research

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Proceedings Article | 18 April 2000 Paper

Paper

New NCI initiatives in computer-aided diagnosis

Laurence Clarke, Barbara Croft, Edward Staab

Proceedings Volume 3976, (2000) https://doi.org/10.1117/12.383061

KEYWORDS: Databases, Computer aided diagnosis and therapy, Standards development, Cancer, Lung cancer, X-ray computed tomography, Lung, Image processing, Software development, Image registration

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SPIE Journal Paper | 1 September 1999

Multiresolution analysis of two-dimensional 1/f processes: approximation methods for random variable transformations

John Heine, Stanley Deans, Deepak Gangadharan, Laurence Clarke

OE, Vol. 38, Issue 09, (September 1999) https://doi.org/10.1117/12.10.1117/1.602201

KEYWORDS: Wavelets, Statistical analysis, Mammography, Optical engineering, Fractal analysis, Image processing, Linear filtering, Fourier transforms, Solids, Bessel functions

Proceedings Article | 21 May 1999 Paper

Paper

Improving mass detection by adaptive and multiscale processing in digitized mammograms

Lihua Li, Wei Qian, Laurence Clarke, Robert Clark, Jerry Thomas

Proceedings Volume 3661, (1999) https://doi.org/10.1117/12.348604

KEYWORDS: Image segmentation, Mammography, Image processing, Cancer, Computer aided design, Breast, Multiscale representation, Tissues, Signal processing, Computer aided diagnosis and therapy

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Proceedings Article | 26 June 1998 Paper

Paper

Digitized mammogram standardization for display and CAD

Robert Velthuizen, Laurence Clarke

Proceedings Volume 3335, (1998) https://doi.org/10.1117/12.312491

KEYWORDS: Mammography, Computer aided design, Computer aided diagnosis and therapy, Genetic algorithms, Databases, Digital mammography, Calibration, Image registration, Absorbance, Radiology

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Proceedings Article | 24 June 1998 Paper

Paper

Image feature extraction for mass detection in digital mammography: effects of wavelet analysis

Lihua Li, Wei Qian, Laurence Clarke

Proceedings Volume 3338, (1998) https://doi.org/10.1117/12.310843

KEYWORDS: Image segmentation, Feature extraction, Statistical analysis, Wavelet transforms, Tissues, Computer aided design, Computer aided diagnosis and therapy, Mammography, Wavelets, Digital mammography

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Proceedings Article | 1 March 1998 Paper

Paper

Computer-assisted diagnostic (CAD) methods for x-ray imaging and teleradiology

Wei Qian, Lihua Li, Laurence Clarke, Fei Mao, Maria Kallergi, Robert Clark, Jerry Thomas

Proceedings Volume 3240, (1998) https://doi.org/10.1117/12.300054

KEYWORDS: Computer aided diagnosis and therapy, Diagnostics, X-ray imaging, Teleradiology, Algorithm development, Wavelet transforms, Image sensors, Detection and tracking algorithms, Mammography, Digital mammography

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Proceedings Article | 7 May 1997 Paper

Paper

Workstation interface for ROC studies in digital mammography

Himanshu Gohel, Maria Kallergi, Michal Vossberg, Marios Gavrielides, Laurence Clarke, Jerry Thomas

Proceedings Volume 3031, (1997) https://doi.org/10.1117/12.273922

KEYWORDS: Digital mammography, Mammography, Computer aided design, Computer aided diagnosis and therapy, Sun, Human-machine interfaces, Control systems, Software development, Image resolution, Visualization

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Proceedings Article | 2 May 1997 Paper

Paper

Evaluation of a CCD-based film digitizer for digital mammography

Maria Kallergi, Marios Gavrielides, William Gross, Laurence Clarke

Proceedings Volume 3032, (1997) https://doi.org/10.1117/12.273995

KEYWORDS: Digital imaging, Spatial resolution, Scanners, Digital mammography, Absorbance, Image resolution, Mammography, Image quality, CCD cameras, Charge-coupled devices

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Proceedings Article | 25 April 1997 Paper

Paper

Automatic shape analysis and classification of mammographic calcifications

Marios Gavrielides, Maria Kallergi, Laurence Clarke

Proceedings Volume 3034, (1997) https://doi.org/10.1117/12.274175

KEYWORDS: Shape analysis, Mammography, Image segmentation, Image resolution, Computer simulations, Spatial resolution, Image classification, Biopsy, Breast cancer, Binary data

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Proceedings Article | 25 April 1997 Paper

Paper

Hybrid adaptive wavelet-based CAD method for mass detection

Wei Qian, Lihua Li, Fei Mao, Laurence Clarke

Proceedings Volume 3034, (1997) https://doi.org/10.1117/12.274166

KEYWORDS: Image segmentation, Wavelets, Wavelet transforms, Digital filtering, Digital imaging, Feature extraction, Computer aided diagnosis and therapy, Computer aided design, Image resolution, Image filtering

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Proceedings Article | 25 April 1997 Paper

Paper

Adaptive segmentation of an x-ray CT image using vector quantization

Lihua Li, Wei Qian, Laurence Clarke

Proceedings Volume 3034, (1997) https://doi.org/10.1117/12.274174

KEYWORDS: Image segmentation, X-ray computed tomography, Brain, Tissues, Tumors, Image processing algorithms and systems, X-rays, X-ray imaging, Quantization, Neuroimaging

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Proceedings Article | 25 April 1997 Paper

Paper

Fractional dimension filtering for multiscale lung nodule detecton

Fei Mao, Wei Qian, Laurence Clarke

Proceedings Volume 3034, (1997) https://doi.org/10.1117/12.274131

KEYWORDS: Lung, Image filtering, Image segmentation, Computer aided design, Computer aided diagnosis and therapy, Chest, Image processing, Nonlinear filtering, Image enhancement, Image classification

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Proceedings Article | 16 April 1996 Paper

Paper

Novel approach to feature extraction for MRI segmentation

Robert Velthuizen, Lawrence Hall, Laurence Clarke

Proceedings Volume 2710, (1996) https://doi.org/10.1117/12.237926

KEYWORDS: Tumors, Feature extraction, Image segmentation, Genetic algorithms, Magnetic resonance imaging, Brain, Feature selection, Associative arrays, Iris recognition, Error analysis

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SPIE Journal Paper | 1 May 1995

Neural network with maximum entropy constraint for nuclear medicine image restoration

Huai Li, Maria Kallergi, Wei Qian, Vijay Jain, Laurence Clarke

OE, Vol. 34, Issue 05, (May 1995) https://doi.org/10.1117/12.10.1117/12.201646

KEYWORDS: Image restoration, Point spread functions, Neurons, Signal to noise ratio, Nuclear medicine, Cameras, Interference (communication), Image processing, Spherical lenses, Neural networks

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Proceedings Article | 27 April 1995 Paper

Paper

Academic consortium for the evaluation of computer-aided diagnosis (CADx) in mammography

Seong Mun, Matthew Freedman, Chris Wu, Shih-Chung Lo, Carey Floyd, Joseph Lo, Heang-Ping Chan, Mark Helvie, Nicholas Petrick, Berkman Sahiner, Datong Wei, Dev Chakraborty, Laurence Clarke, Maria Kallergi, Bob Clark, Yongmin Kim

Proceedings Volume 2431, (1995) https://doi.org/10.1117/12.207638

KEYWORDS: Computer aided diagnosis and therapy, Mammography, Computing systems, Algorithm development, Breast cancer, Databases, Optimization (mathematics), Cancer, Digital mammography, Detection and tracking algorithms

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Proceedings Article | 11 May 1994 Paper

Paper

Fuzzy cluster validity in magnetic resonance images

Amine Bensaid, Lawrence Hall, James Bezdek, Laurence Clarke

Proceedings Volume 2167, (1994) https://doi.org/10.1117/12.175079

KEYWORDS: Fuzzy logic, Image segmentation, Magnetic resonance imaging, Tissues, Image processing, Magnetism, Neuroimaging, Brain, Image processing algorithms and systems, Detection and tracking algorithms

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Proceedings Article | 29 July 1993 Paper

Paper

Unsupervised fuzzy segmentation of 3D magnetic resonance brain images

Robert Velthuizen, Lawrence Hall, Laurence Clarke, Amine Bensaid, J. Arrington, Martin Silbiger

Proceedings Volume 1905, (1993) https://doi.org/10.1117/12.148675

KEYWORDS: Image segmentation, Tissues, Tumors, Brain, Fuzzy logic, 3D image processing, Magnetic resonance imaging, Neuroimaging, Magnetism, Pattern recognition

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Proceedings Article | 29 July 1993 Paper

Paper

Tree-structured nonlinear filter and wavelet transform for microcalcification segmentation in mammography

Wei Qian, Laurence Clarke, Maria Kallergi, Huai Li, Robert Velthuizen, Robert Clark, Martin Silbiger

Proceedings Volume 1905, (1993) https://doi.org/10.1117/12.148665

KEYWORDS: Digital filtering, Image filtering, Nonlinear filtering, Wavelets, Image enhancement, Wavelet transforms, Feature extraction, Mammography, Image processing, Electronic filtering

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Proceedings Article | 29 July 1993 Paper

Paper

Comparative evaluation of pattern recognition techniques for detection of microcalcifications

Kevin Woods, Jeffrey Solka, Carey Priebe, Chris Doss, Kevin Bowyer, Laurence Clarke

Proceedings Volume 1905, (1993) https://doi.org/10.1117/12.148696

KEYWORDS: Image segmentation, Error analysis, Mammography, Image classification, Pattern recognition, Neural networks, Detection and tracking algorithms, Feature extraction, Data acquisition, Data modeling

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Proceedings Article | 1 July 1992 Paper

Paper

Partially supervised fuzzy c-means algorithm for segmentation of MR images

Amine Bensaid, James Bezdek, Lawrence Hall, Robert Velthuizen, Laurence Clarke

Proceedings Volume 1710, (1992) https://doi.org/10.1117/12.140120

KEYWORDS: Image segmentation, Tissues, Magnetic resonance imaging, Tumors, Detection and tracking algorithms, Image classification, Fuzzy logic, Image processing algorithms and systems, Data centers, Artificial neural networks

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Proceedings Article | 1 June 1992 Paper

Paper

Bremsstrahlung imaging with the gamma camera

Maria Kallergi, Wei Qian, Laurence Clarke, Allan Gondeck

Proceedings Volume 1651, (1992) https://doi.org/10.1117/12.59399

KEYWORDS: Collimators, Image filtering, Cameras, Optical filters, Digital filtering, Tomography, Image restoration, Medical imaging, Nonlinear filtering, Signal attenuation

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Proceedings Article | 1 June 1992 Paper

Paper

Application of nonlinear filtering in mammograms

Wei Qian, Maria Kallergi, Laurence Clarke, Kevin Woods, Robert Clark

Proceedings Volume 1652, (1992) https://doi.org/10.1117/12.59476

KEYWORDS: Digital filtering, Nonlinear filtering, Image filtering, Breast, Image segmentation, Linear filtering, Edge detection, Image processing, Dysprosium, Mammography

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Proceedings Article | 1 June 1992 Paper

Paper

Comparison of supervised pattern recognition techniques and unsupervised methods for MRI segmentation

Laurence Clarke, Robert Velthuizen, Lawrence Hall, James Bezdek, Amine Bensaid, Martin Silbiger

Proceedings Volume 1652, (1992) https://doi.org/10.1117/12.59477

KEYWORDS: Image segmentation, Tissues, Pattern recognition, Magnetic resonance imaging, Medical imaging, Fuzzy logic, Image processing, 3D displays, 3D image processing, Pathology

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Showing 5 of 27 publications

Conference Committee Involvement (5)

Multimodal Biomedical Imaging III

19 January 2008 | San Jose, California, United States

Multimodal Biomedical Imaging II

20 January 2007 | San Jose, California, United States

Optical Imaging 2006

25 September 2006 | Bethesda, Maryland, United States

Multimodal Biomedical Imaging

21 January 2006 | San Jose, California, United States

Optical Imaging 2004

20 September 2004 | Washington, DC, United States

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