In the field of Biomedical Optics, understanding how transparent layers affect light propagation in tissue is crucial for optimizing therapeutic and diagnostic applications. We employed Monte Carlo simulation to analyze changes in light behavior when introducing a transparent layer onto a multilayer optical skin phantom. Our study revealed that adding a transparent layer alters the illuminated volume, with changes influenced by the refractive index and thickness of the layer. This insight emphasizes the significance of both composition and thickness of transparent materials in influencing light propagation within the skin model. Such knowledge is fundamental for improving light-based therapies and diagnostics in Biomedical Optics.
Photobiomodulation (PBM) utilizes light to stimulate cellular responses in medical and therapeutic fields. This study investigates how light probe design influences tissue penetration. Factors like spot size, geometry, and materials were explored. Monte Carlo simulations and experiments were performed in tissue phantoms and volunteers. Results reveal how probe design optimization can enhance PBM's safety and efficacy, providing insights for personalized treatment protocols. Understanding light interactions in biological tissues is vital for tailoring therapy to individual patients and specific equipment.
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