As the world ages, the prevalence of knee osteoarthritis is increasing every year. The most effective treatment option for this disease in its later stages is currently considered to be total knee arthroplasty (TKA). The growing computer-aided engineering technology has contributed to TKA surgical success rates by conducting Finite Element Analysis (FEA). Nevertheless, there is still room for improvement in post-operative satisfaction rates for TKA. Several studies have made research on the application and computational analysis of FEA for specific devices and particular processes in TKA. However, very limited studies have considered how to aggregate and expand the role of FEA into the whole surgery process. This study provides a systematic analysis of the application of FEA in joint replacement, especially TKA. For this purpose, the concept of general engineering is mentioned to perform a preoperative planning model and workflow. The study has concluded the present research status of Finite Element Analysis in TKA as well as depicted the PGE workflow as a suggestion for subsequent research in this area.
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