Ocular rigidity in diabetic retinopathy using optical coherence tomography

Yanhui Ma; Cynthia J. Roberts

doi:10.1117/12.2610214

2 March 2022 Ocular rigidity in diabetic retinopathy using optical coherence tomography

Yanhui Ma, Cynthia J. Roberts

Proceedings Volume PC11962, Optical Elastography and Tissue Biomechanics VIV; PC119620B (2022) https://doi.org/10.1117/12.2610214
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Diabetic retinopathy, a slow progressive complication of diabetes, is the leading cause of vision impairment and blindness among working-age adults. In the presence of hyperglycemia, ocular tissues become stiffer in response to the increased non-enzymatic cross-linking of collagen fibrils. Ocular rigidity may serve as a cumulative response indicator of hyperglycemia. We have implemented an in vivo approach to estimate ocular rigidity using dynamic optical coherence tomography, which allowed us to investigate the diabetic retinopathy-associated biomechanical changes in a clinical setting.

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Citation Download Citation

Yanhui Ma and Cynthia J. Roberts "Ocular rigidity in diabetic retinopathy using optical coherence tomography", Proc. SPIE PC11962, Optical Elastography and Tissue Biomechanics VIV, PC119620B (2 March 2022); https://doi.org/10.1117/12.2610214

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