Jiawen Lihttps://orcid.org/0000-0001-8818-6070,1 Simon Thiele,2 Pavel Puchka,2 Andrea Toulouse,2 Rodney Kirk,1 Bryden Quirk,1 Ayla Hoogendoorn,3 Yung Chin Chen,4 Karlheinz Peter,4 Emma Akers,3 Stephen Nicholls,5 Johan Verjans,3 Peter Psaltis,3 Christina Bursill,3 Alois Herkommer,2 Harald Giessen,2 Robert McLaughlin1
1The Univ. of Adelaide (Australia) 2Univ. Stuttgart (Germany) 3South Australian Health and Medical Research Institute (SAHMRI) (Australia) 4Baker Heart and Diabetes Institute (Australia) 5Monash Univ. (Australia)
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Preclinical studies and clinical diagnostics increasingly rely on optical techniques to visualize internal organs. Miniaturised catheters or endoscopes are necessary for imaging small and/or delicate arteries. However, current lens fabrication methods limit the performance of these ultrathin devices, resulting in a poor combination of resolution, depth of focus and multimodal imaging capability. This talk will introduce our latest research to address these combined challenges. In particular, we have utilized 3D micro-printing technology to fabricate freeform optics directly onto an optical fiber to achieve freeform designs for aberration-corrected optical coherence tomography (OCT) and to enable highly-sensitive multimodal fluorescence+OCT imaging in vivo.
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Jiawen Li, Simon Thiele, Pavel Puchka, Andrea Toulouse, Rodney Kirk, Bryden Quirk, Ayla Hoogendoorn, Yung Chin Chen, Karlheinz Peter, Emma Akers, Stephen Nicholls, Johan Verjans, Peter Psaltis, Christina Bursill, Alois Herkommer, Harald Giessen, Robert McLaughlin, "Ultrathin 3D-printed intravascular imaging catheters," Proc. SPIE PC12355, Diagnostic and Therapeutic Applications of Light in Cardiology 2023, PC1235503 (17 March 2023); https://doi.org/10.1117/12.2660627