Presentation
13 March 2024 A novel capsule endoscope for immuno-OCT imaging in the gastrointestinal tract
Tyla Danskin, Andrea J. Sterkenburg, Wouter B. Nagengast, Johannes F. de Boer
Author Affiliations +
Proceedings Volume PC12820, Endoscopic Microscopy XIX; PC128200C (2024) https://doi.org/10.1117/12.3003001
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Optical Coherence Tomography (OCT) acquires micron-resolution depth information on the superficial layers of tissues, but lacks in molecular specificity. Near Infrared Fluorescence (NIRF) imaging in combination with fluorescently labelled monoclonal antibodies can provide micron-resolution molecular contrast (Immuno-OCT). Here, a novel capsule endoscope design is presented, which facilitates circumferential imaging in the gastrointestinal tract. The endoscope is fitted with a double clad fiber coupler to enable dual-modality imaging. We present preliminary endoscopic data for both imaging modalities, for which phantoms were used to validate the capsule endoscope as an Immuno-OCT imaging device.
Conference Presentation
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Tyla Danskin, Andrea J. Sterkenburg, Wouter B. Nagengast, and Johannes F. de Boer "A novel capsule endoscope for immuno-OCT imaging in the gastrointestinal tract", Proc. SPIE PC12820, Endoscopic Microscopy XIX, PC128200C (13 March 2024); https://doi.org/10.1117/12.3003001
Advertisement
Advertisement
KEYWORDS
Endoscopes

Optical coherence tomography

Coherence imaging

Fluorescence

Near infrared

Tissues

Optical coherence

Back to Top