Methods and means of 3D diffuse Mueller-matrix tomography of depolarizing optically anisotropic biological layers

O. V. Dubolazov; V. O. Ushenko; L. Trifoniuk; Yu. O. Ushenko; V. G. Zhytaryuk; O. G. Prydiy; M. Grytsyuk; L. Kushnerik; I. Meglinskiy

doi:10.1117/12.2273817

19 September 2017 Methods and means of 3D diffuse Mueller-matrix tomography of depolarizing optically anisotropic biological layers

O. V. Dubolazov, V. O. Ushenko, L. Trifoniuk, Yu. O. Ushenko, V. G. Zhytaryuk, O. G. Prydiy, M. Grytsyuk, L. Kushnerik, I. Meglinskiy

Author Affiliations +

Proceedings Volume 10396, Applications of Digital Image Processing XL; 103962P (2017) https://doi.org/10.1117/12.2273817
Event: SPIE Optical Engineering + Applications, 2017, San Diego, California, United States

Abstract

A new technique of Mueller-matrix mapping of polycrystalline structure of histological sections of biological tissues is suggested. The algorithms of reconstruction of distribution of parameters of linear and circular birefringence of prostate histological sections are found. The interconnections between such distributions and parameters of linear and circular birefringence of prostate tissue histological sections are defined. The comparative investigations of coordinate distributions of phase anisotropy parameters formed by fibrillar networks of prostate tissues of different pathological states (adenoma and carcinoma) are performed. The values and ranges of change of the statistical (moments of the 1st – 4th order) parameters of coordinate distributions of the value of linear and circular birefringence are defined. The objective criteria of cause of Benign and malignant conditions differentiation are determined.

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O. V. Dubolazov, V. O. Ushenko, L. Trifoniuk, Yu. O. Ushenko, V. G. Zhytaryuk, O. G. Prydiy, M. Grytsyuk, L. Kushnerik, and I. Meglinskiy "Methods and means of 3D diffuse Mueller-matrix tomography of depolarizing optically anisotropic biological layers", Proc. SPIE 10396, Applications of Digital Image Processing XL, 103962P (19 September 2017); https://doi.org/10.1117/12.2273817

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