The photophysics of non-genetic opto stimulation (Conference Presentation)

Guglielmo Lanzani

doi:10.1117/12.2320405

18 September 2018 The photophysics of non-genetic opto stimulation (Conference Presentation)

Guglielmo Lanzani

Proceedings Volume 10738, Organic and Hybrid Sensors and Bioelectronics XI; 107380W (2018) https://doi.org/10.1117/12.2320405
Event: SPIE Organic Photonics + Electronics, 2018, San Diego, California, United States

Abstract

Organic semiconductors in different shapes and composition can be interfaced with living cells. This provides a new, exciting route towards optical control of physiological functions or the restoring of natural functions, e.g. vision. In this talk I will present a number of experiments that show the effective abiotic-biotic coupling of organic semiconductors with cells and small animals, suggesting the potential of organic light actuators for geneless opto stimulation. Investigated systems are all based on polythiophene as photoactive layer, in planar films, nanostructured layers or nanoparticles. Spectroscopy, photo-electrochemistry and photo-electrophysiology are exploited to carry out the experimental investigations. We report on photoluminescence in vivo of nanoparticles and other light actuators. While the mechanism explaining such coupling is still unknown, it is appearing that thermal, capacitive, faradaic or chemical coupling are all options to be carefully evaluated.

Conference Presentation

Citation Download Citation

Guglielmo Lanzani "The photophysics of non-genetic opto stimulation (Conference Presentation)", Proc. SPIE 10738, Organic and Hybrid Sensors and Bioelectronics XI, 107380W (18 September 2018); https://doi.org/10.1117/12.2320405

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