Diffusive laser tomography of multilateral biological tissues

M. Yu. Sakhnovskiy; A. V. Dubolazov; V. A. Ushenko; S. O. Sokolnuik; P. M. Grygoryshyn; O. Ya. Vanchuliak; M. I. Sidor; R. M. Besaga

doi:10.1117/12.2323583

31 December 2018 Diffusive laser tomography of multilateral biological tissues

M. Yu. Sakhnovskiy, A. V. Dubolazov, V. A. Ushenko, S. O. Sokolnuik, P. M. Grygoryshyn, O. Ya. Vanchuliak, M. I. Sidor, R. M. Besaga

Author Affiliations +

Proceedings Volume 10977, Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies IX; 109773Q (2018) https://doi.org/10.1117/12.2323583
Event: Advanced Topics in Optoelectronics, Microelectronics and Nanotechnologies IX, 2018, Constanta, Romania

Abstract

The 3D Muller-matrix mapping of map depolarization depolarizing layers of biological tissues of different morphological structure and physiological state is proposed and substantiated. 3D maps of depolarization of optically thick histological sections of myocardium tissue with spatially structured optically anisotropic fibrillary network, as well as parenchymatous rat liver tissue with “islet” polycrystalline structure were obtained. The dependences of the magnitude of the statistical moments of the 1st-4th order, which characterize the layered distributions of the degree of depolarization of different types of biological tissues, are determined. The study of the possibilities of differentiation of benign (adenoma) and malignant (carcinoma) changes of histological sections of the tissue of the uterine tissue biopsy was conducted. In addition, the possibility of diagnosing the degree of blood loss in the liver was investigated. The dependences of the magnitude of the statistical moments of the first and fourth orders, which characterize layer-by-layer distributions of the values of the degree of depolarization of various types of biological tissues are determined. The possibility of differentiation of benign (adenoma) and malignant (carcinoma) changes in the histological sections of the biopsy of the uterus wall tissue was studied. In addition, the possibility of diagnosing the degree of hepatic blood loss was investigated.

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M. Yu. Sakhnovskiy, A. V. Dubolazov, V. A. Ushenko, S. O. Sokolnuik, P. M. Grygoryshyn, O. Ya. Vanchuliak, M. I. Sidor, and R. M. Besaga "Diffusive laser tomography of multilateral biological tissues", Proc. SPIE 10977, Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies IX, 109773Q (31 December 2018); https://doi.org/10.1117/12.2323583

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