Deep variational autoencoders for breast cancer tissue modeling and synthesis in SFDI

Arturo Pardo; José M. López-Higuera; Brian W. Pogue; Olga M. Conde

doi:10.1117/12.2527142

11 July 2019 Deep variational autoencoders for breast cancer tissue modeling and synthesis in SFDI

Arturo Pardo, José M. López-Higuera, Brian W. Pogue, Olga M. Conde

Proceedings Volume 11074, Diffuse Optical Spectroscopy and Imaging VII; 110741G (2019) https://doi.org/10.1117/12.2527142
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

Extracting pathology information embedded within surface optical properties in Spatial Frequency Domain Imaging (SFDI) datasets is still a rather cumbersome nonlinear translation problem, mainly constrained by intrasample and interpatient variability, as well as dataset size. The β-variational autoencoder (β-VAE) is a rather novel dimensionality reduction technique where a tractable set of latent low-dimensional embeddings can be obtained from a given dataset. These embeddings can then be sampled to synthesize new data, providing further insight into pathology variability as well as differentiability in terms of optical properties. Its applications for data classification and breast margin delineation are also discussed.

Citation Download Citation

Arturo Pardo, José M. López-Higuera, Brian W. Pogue, and Olga M. Conde "Deep variational autoencoders for breast cancer tissue modeling and synthesis in SFDI", Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 110741G (11 July 2019); https://doi.org/10.1117/12.2527142

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