Applications for compressed ultrafast photography to biological imaging and sensing

Joel N. Bixler; Allen Keister; Zach Coker; Bennett L. Ibey

doi:10.1117/12.2540049

30 December 2019 Applications for compressed ultrafast photography to biological imaging and sensing

Joel N. Bixler, Allen Keister, Zach Coker, Bennett L. Ibey

Proceedings Volume 11202, Biophotonics Australasia 2019; 1120204 (2019) https://doi.org/10.1117/12.2540049
Event: ANZCOP, 2019, Melbourne, Australia

Abstract

Compressed ultrafast photography (CUP) is a new imaging technique which incorporates the high-speed imaging capabilities of a streak camera with principles from compressed sensing to allow for single-shot, ultrafast imaging of optical phenomena at up to 100 billion frames per second¹. While this technique has primarily been utilized to observe physical phenomena, it has broad ranging application to biological imaging including fluorescence lifetime microscopy, and single-shot hyperspectral imaging². Additionally, similar optical systems can be used to for streak camera microscopy (SCM), enabling the resolution of sub microsecond changes in cellular membrane potential in response to electrical stimulation³. Here, we present several applications for CUP based imaging and spectroscopy as a novel tool to enable more rapid biological imaging and sensing.

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Joel N. Bixler, Allen Keister, Zach Coker, and Bennett L. Ibey "Applications for compressed ultrafast photography to biological imaging and sensing", Proc. SPIE 11202, Biophotonics Australasia 2019, 1120204 (30 December 2019); https://doi.org/10.1117/12.2540049

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KEYWORDS

Ultrafast imaging

Photography

Streak cameras

Biosensing

Hyperspectral imaging

Argon ion lasers

Imaging systems

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