Dual-mode endoscopic probe combining OCT and autofluorescence imaging for inner ear hearing loss diagnosis and therapy guidance (Conference Presentation)

Jesung Park; Jeffrey T. Cheng; Daniel Lee; Jeffrey Holt; Hannah Goldberg; Gopi N. Maguluri; John Grimble; Nicusor V. Iftimia

doi:10.1117/12.2542678

6 March 2020 Dual-mode endoscopic probe combining OCT and autofluorescence imaging for inner ear hearing loss diagnosis and therapy guidance (Conference Presentation)

Jesung Park, Jeffrey T. Cheng, Daniel Lee, Jeffrey Holt, Hannah Goldberg, Gopi N. Maguluri, John Grimble, Nicusor V. Iftimia

Author Affiliations +

Proceedings Volume 11213, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2020; 1121303 (2020) https://doi.org/10.1117/12.2542678
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

This study presents a novel technology for in vivo cochlear imaging in sensorineural hearing loss (SNHL). SNHL is the most common type of permanent hearing loss and is associated with damaged hair cells of the cochlea. State of the art clinical imaging does not have sufficient resolution to show inner ear microstructure. We are developing and testing a dual-modal endoscopic instrument that combines optical coherence tomography (OCT) and autofluorescence imaging (AFI) for dynamic cochlear imaging. If successful, this approach will improve our understanding of the cellular basis of SNHL and enable the development of targeted therapies for inner ear disorders.

Conference Presentation

Citation Download Citation

Jesung Park, Jeffrey T. Cheng, Daniel Lee, Jeffrey Holt, Hannah Goldberg, Gopi N. Maguluri, John Grimble, and Nicusor V. Iftimia "Dual-mode endoscopic probe combining OCT and autofluorescence imaging for inner ear hearing loss diagnosis and therapy guidance (Conference Presentation)", Proc. SPIE 11213, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2020, 1121303 (6 March 2020); https://doi.org/10.1117/12.2542678

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