10 March 2020Optimization of a plasmonic fluorescence biosensor platform to detect serum antibodies with high sensitivity and consistency (Conference Presentation)
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
Detection of antibodies in the blood is an important clinical technique for diagnosing active infections and previous exposures. The grating-coupled fluorescent plasmonics (GC-FP) biosensing platform has been used to detect Lyme disease serum antibodies in patients and has been shown to be more sensitive than the current standard tests. In this study, we sought to design an affordable GC-FP detection system without sacrificing the sensitivity of data output. We further optimized our analysis strategies to achieve highly sensitive and consistent diagnostic results. This work ultimately aims to fill an unmet need for better detection of human Lyme disease.
Eunice Chou,Arturo Pilar,Ernest Guignon,William Page,George Gibson,Yi-Pin Lin, andNathaniel C. Cady
"Optimization of a plasmonic fluorescence biosensor platform to detect serum antibodies with high sensitivity and consistency (Conference Presentation)", Proc. SPIE 11258, Frontiers in Biological Detection: From Nanosensors to Systems XII, 1125806 (10 March 2020); https://doi.org/10.1117/12.2551067
ACCESS THE FULL ARTICLE
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
The alert did not successfully save. Please try again later.
Eunice Chou, Arturo Pilar, Ernest Guignon, William Page, George Gibson, Yi-Pin Lin, Nathaniel C. Cady, "Optimization of a plasmonic fluorescence biosensor platform to detect serum antibodies with high sensitivity and consistency (Conference Presentation)," Proc. SPIE 11258, Frontiers in Biological Detection: From Nanosensors to Systems XII, 1125806 (10 March 2020); https://doi.org/10.1117/12.2551067