Lensfree super-resolved microscopy based on multi-wavelength multiplexing

Xuejuan Wu; Linpeng Lu; Jialin Zhang; Jiasong Sun; Qian Chen; Chao Zuo

doi:10.1117/12.2573373

10 October 2020 Lensfree super-resolved microscopy based on multi-wavelength multiplexing

Xuejuan Wu, Linpeng Lu, Jialin Zhang, Jiasong Sun, Qian Chen, Chao Zuo

Proceedings Volume 11549, Advanced Optical Imaging Technologies III; 1154904 (2020) https://doi.org/10.1117/12.2573373
Event: SPIE/COS Photonics Asia, 2020, Online Only

Abstract

In this paper, we present a multi-wavelength multiplexed setup and associated super-resolution reconstruction method in lensfree microscopy that generates high-resolution reconstructions from undersampled raw measurements captured at multiple wavelengths. The reconstruction result of the standard 1951 USAF achieves a half-pitch lateral resolution of 775 nm, corresponding to a numerical aperture of 1.0, across a large field of view (∼ 29.85 mm²). Compared with other super-resolution methods such as lateral or axial shift-based device and illumination source rotation design, wavelength multiplexed avoids the need for shifting/rotating mechanical components. This multi-wavelength multiplexed super-resolution method would benefit the research and development of a more stable lensfree microscopy system.

Conference Presentation

Citation Download Citation

Xuejuan Wu, Linpeng Lu, Jialin Zhang, Jiasong Sun, Qian Chen, and Chao Zuo "Lensfree super-resolved microscopy based on multi-wavelength multiplexing", Proc. SPIE 11549, Advanced Optical Imaging Technologies III, 1154904 (10 October 2020); https://doi.org/10.1117/12.2573373

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