Holographic lensless quantitative phase imaging microscope

Linpeng Lu; Xiangyu Zhang; Jiasong Sun; Jialin Zhang; Yao Fan; Qian Chen; Chao Zuo

doi:10.1117/12.2580516

7 October 2020 Holographic lensless quantitative phase imaging microscope

Linpeng Lu, Xiangyu Zhang, Jiasong Sun, Jialin Zhang, Yao Fan, Qian Chen, Chao Zuo

Proceedings Volume 11571, Optics Frontier Online 2020: Optics Imaging and Display; 1157111 (2020) https://doi.org/10.1117/12.2580516
Event: Optics Frontiers Online 2020: Optics Imaging and Display (OFO-1), 2020, Shanghai, China

Abstract

In this paper, a holographic lensless quantitative phase imaging (QPI) microscope is presented, which is composed of a CMOS detector image sensor with a programmable color LED matrix, without any lens and mechanical displacement device. Such a miniaturized system can provide a field-portable cost-effective platform for highthroughput quantification of multiple samples. Coordinating the self-developed software operating system, the bright-field imaging, the quantitative phase imaging as well as cell counting, profile analysis, three-dimensional (3D) imaging and differential interference contrast (DIC) imaging can be realized. With its high-resolution based computational microscopy interface, this system can be also adaptively used for telemedicine applications and point-of-care testing (POCT) in resource-limited environments.

Citation Download Citation

Linpeng Lu, Xiangyu Zhang, Jiasong Sun, Jialin Zhang, Yao Fan, Qian Chen, and Chao Zuo "Holographic lensless quantitative phase imaging microscope", Proc. SPIE 11571, Optics Frontier Online 2020: Optics Imaging and Display, 1157111 (7 October 2020); https://doi.org/10.1117/12.2580516

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