Three-dimensional visualization of ductal carcinoma in situ and usual ductal hyperplasia using the refraction-contrast x-ray computed tomography

Kana Taniguchi; Naoki Sunaguchi; Shu Ichihara; Rieko Nishimura; Akari Iwakoshi; Daisuke Shimao; Tetsuya Yuasa; Masami Ando

doi:10.1117/12.2581906

15 February 2021 Three-dimensional visualization of ductal carcinoma in situ and usual ductal hyperplasia using the refraction-contrast x-ray computed tomography

Kana Taniguchi, Naoki Sunaguchi, Shu Ichihara, Rieko Nishimura, Akari Iwakoshi, Daisuke Shimao, Tetsuya Yuasa, Masami Ando

Author Affiliations +

Proceedings Volume 11600, Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging; 116001T (2021) https://doi.org/10.1117/12.2581906
Event: SPIE Medical Imaging, 2021, Online Only

Conference Poster

Abstract

We visualized the luminal structures generated by DCIS and UDH using a refraction-contrast X-ray CT technique, which provides a contrast close to stained tissue images, and showed that DCIS and UDH forms a bubble-like shape and a tube-like shape, respectively. To express the difference in the three-dimensional structure between these tissue clearly, the number of luminal spaces, luminal volume, luminal density, and path length of the luminal structures were introduced. As a result, it was found that DCIS has many smaller and shorter lumens than UDH, which can contribute to the development of 3D pathology.

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Kana Taniguchi, Naoki Sunaguchi, Shu Ichihara, Rieko Nishimura, Akari Iwakoshi, Daisuke Shimao, Tetsuya Yuasa, and Masami Ando "Three-dimensional visualization of ductal carcinoma in situ and usual ductal hyperplasia using the refraction-contrast x-ray computed tomography", Proc. SPIE 11600, Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging, 116001T (15 February 2021); https://doi.org/10.1117/12.2581906

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