Dual-wavelength photo-killing of methicillin resistant staphylococcus aureus

Leon G. Leanse; Xueping Sharon Goh; Ji-Xin Cheng; David C. Hooper; Tianhong Dai

doi:10.1117/12.2577202

5 March 2021 Dual-wavelength photo-killing of methicillin resistant staphylococcus aureus

Leon G. Leanse, Xueping Sharon Goh, Ji-Xin Cheng, David C. Hooper, Tianhong Dai

Proceedings Volume 11626, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2021; 116260T (2021) https://doi.org/10.1117/12.2577202
Event: SPIE BiOS, 2021, Online Only

Abstract

Antimicrobial resistance is a concern to public health, with methicillin resistant Staphylococcus aureus (MRSA) being particularly important. Blue light at 405 nm has demonstrated efficacy for the treatment of localized infections. With respect to MRSA, aBL is not effective enough to be developed into a stand-alone therapy. Findings demonstrated the antioxidant properties of the S. aureus pigment, staphyloxanthin (STX). We hypothesized that the efficacy of 405 nm light on MRSA may improve with STX photolysis using 460 nm light. We report an approach that exploits the STX photolysis effect of 460 nm light to sensitize MRSA to 405 nm light.

Conference Presentation

Citation Download Citation

Leon G. Leanse, Xueping Sharon Goh, Ji-Xin Cheng, David C. Hooper, and Tianhong Dai "Dual-wavelength photo-killing of methicillin resistant staphylococcus aureus", Proc. SPIE 11626, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2021, 116260T (5 March 2021); https://doi.org/10.1117/12.2577202

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Cell death

In vivo imaging

Oxygen

Photolysis

Skin

Organisms

Photomedicine

Show All Keywords

Keywords/Phrases

Search In:

Publication Years