Investigation of frequency domain high-density diffuse optical tomography on whole subject-based head model

Weihao Fan; Hamid Dehghani; Adam T. Eggebrecht

doi:10.1117/12.2577316

5 March 2021 Investigation of frequency domain high-density diffuse optical tomography on whole subject-based head model

Weihao Fan, Hamid Dehghani, Adam T. Eggebrecht

Author Affiliations +

Proceedings Volume 11629, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics; 116290T (2021) https://doi.org/10.1117/12.2577316
Event: SPIE BiOS, 2021, Online Only

Abstract

We provide herein a simulation study of the effects of modulation frequency on the image quality obtainable with frequency domain high density diffuse optical tomography. Using an anatomical head model, we simulated point spread functions with modulation frequencies spanning 0-1,000 MHz throughout the optically accessible field of view. We assessed image quality using metrics of the full width at half maximum, the localization error, and the 50% success rate. Our results show higher modulation frequency improves image quality and provides access to deeper brain tissue.

Conference Presentation

Citation Download Citation

Weihao Fan, Hamid Dehghani, and Adam T. Eggebrecht "Investigation of frequency domain high-density diffuse optical tomography on whole subject-based head model", Proc. SPIE 11629, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics, 116290T (5 March 2021); https://doi.org/10.1117/12.2577316

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