Combination of two-photon microscopy and optical coherence tomography with fully fiber-based lasers for future endoscopic setups

Philipp Lamminger; Merle Loop; Julian Klee; Daniel Weng; Jan Philip Kolb; Matthias Strauch; Sebastian Karpf; Robert Huber

doi:10.1117/12.2578679

5 March 2021 Combination of two-photon microscopy and optical coherence tomography with fully fiber-based lasers for future endoscopic setups

Philipp Lamminger, Merle Loop, Julian Klee, Daniel Weng, Jan Philip Kolb, Matthias Strauch, Sebastian Karpf, Robert Huber

Author Affiliations +

Proceedings Volume 11634, Multimodal Biomedical Imaging XVI; 1163405 (2021) https://doi.org/10.1117/12.2578679
Event: SPIE BiOS, 2021, Online Only

Abstract

We present a combination of sub-nanosecond two-photon microscopy (TPM) and megahertz-rate optical coherence tomography (MHz-OCT) via a double ferrule for future endoscopic setups. The double ferrule combines a Hi1060 fiber of the OCT system and a double cladding (DC) fiber of the TPM setup. The use of sub-nanosecond pulses for TPM simplifies the setup substantially as no dispersion management is required. The inner cladding of the DC fiber collects the fluorescent light. The double ferrule was tested in a microscope setup. We characterized our system and collected first imaging data.

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Citation Download Citation

Philipp Lamminger, Merle Loop, Julian Klee, Daniel Weng, Jan Philip Kolb, Matthias Strauch, Sebastian Karpf, and Robert Huber "Combination of two-photon microscopy and optical coherence tomography with fully fiber-based lasers for future endoscopic setups", Proc. SPIE 11634, Multimodal Biomedical Imaging XVI, 1163405 (5 March 2021); https://doi.org/10.1117/12.2578679

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