A low-cost LED-based multispectral capillaroscopy system for oximetry of the nailfold

Michaela Taylor-Williams; Steven Mead; Travis W. Sawyer; Lina Hacker; Calum Williams; Michael Berks; Andrea Murray; Sarah E. Bohndiek

doi:10.1117/12.2575869

5 March 2021 A low-cost LED-based multispectral capillaroscopy system for oximetry of the nailfold

Michaela Taylor-Williams, Steven Mead, Travis W. Sawyer, Lina Hacker, Calum Williams, Michael Berks, Andrea Murray, Sarah E. Bohndiek

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Proceedings Volume 11651, Optical Diagnostics and Sensing XXI: Toward Point-of-Care Diagnostics; 116510J (2021) https://doi.org/10.1117/12.2575869
Event: SPIE BiOS, 2021, Online Only

Abstract

Nailfold capillaroscopy is a technique for imaging the capillary bed in the finger nailfold, that is used in the diagnosis of scleroderma. Knowledge of the capillary oxygenation profile would be a substantial advantage in disease evaluation. A compact, low-cost LED-illuminated capillaroscopy system was conceived based on inexpensive parts and optical hardware. The system uses a compact Raspberry Pi to control a custom-designed LED ring light, with white-light LEDs interleaved with three narrowband LEDs, and a Raspberry Pi camera. Capillary visualisation and distinction of haemoglobin contrast is demonstrated, suggesting future promise for application of multispectral nailfold capillaroscopy in low-resource settings.

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Michaela Taylor-Williams, Steven Mead, Travis W. Sawyer, Lina Hacker, Calum Williams, Michael Berks, Andrea Murray, and Sarah E. Bohndiek "A low-cost LED-based multispectral capillaroscopy system for oximetry of the nailfold", Proc. SPIE 11651, Optical Diagnostics and Sensing XXI: Toward Point-of-Care Diagnostics, 116510J (5 March 2021); https://doi.org/10.1117/12.2575869

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KEYWORDS

Light emitting diodes

Capillaries

Oximetry

Control systems

Hypoxia

Imaging systems

Modeling

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