Surface chemistry-mediated metal nanoclusters for in vivo shortwave infrared imaging

Xavier Le Guével; Benjamin Musnier; K. David Wegner; Maxime Henry; Agnès Desroches-Castan; Ute Resch-Genger; Sabine Bailly; Yves Usson; Véronique Josserand; Jean-Luc Coll

doi:10.1117/12.2577451

5 March 2021 Surface chemistry-mediated metal nanoclusters for in vivo shortwave infrared imaging

Xavier Le Guével, Benjamin Musnier, K. David Wegner, Maxime Henry, Agnès Desroches-Castan, Ute Resch-Genger, Sabine Bailly, Yves Usson, Véronique Josserand, Jean-Luc Coll

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Proceedings Volume 11659, Colloidal Nanoparticles for Biomedical Applications XVI; 116590C (2021) https://doi.org/10.1117/12.2577451
Event: SPIE BiOS, 2021, Online Only

Abstract

We present a method of high resolution, non-invasive, in vivo vascular imaging obtained using watersoluble and bright SWIR-emitting gold nanoclusters presenting an anisotropic surface charge combined with SWIR detection and Monte Carlo processing of the images. We applied this approach to quantify vessel complexity in mice presenting vascular disorders.

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Xavier Le Guével, Benjamin Musnier, K. David Wegner, Maxime Henry, Agnès Desroches-Castan, Ute Resch-Genger, Sabine Bailly, Yves Usson, Véronique Josserand, and Jean-Luc Coll "Surface chemistry-mediated metal nanoclusters for in vivo shortwave infrared imaging", Proc. SPIE 11659, Colloidal Nanoparticles for Biomedical Applications XVI, 116590C (5 March 2021); https://doi.org/10.1117/12.2577451

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