Photonic metamaterial surfaces for digital resolution biosensor microscopies using enhanced absorption, scattering, and emission

Brian T. Cunningham; Taylor D. Canady; Bin Zhao; Shreya Ghosh; Nantao Li; Qinglan Huang; Yanyu Xiong; Glenn Fried; Manish Kohli; Utkan Demirci; Xing Wang

doi:10.1117/12.2579584

5 March 2021 Photonic metamaterial surfaces for digital resolution biosensor microscopies using enhanced absorption, scattering, and emission

Brian T. Cunningham, Taylor D. Canady, Bin Zhao, Shreya Ghosh, Nantao Li, Qinglan Huang, Yanyu Xiong, Glenn Fried, Manish Kohli, Utkan Demirci, Xing Wang

Author Affiliations +

Proceedings Volume 11663, Integrated Sensors for Biological and Neural Sensing; 116630K (2021) https://doi.org/10.1117/12.2579584
Event: SPIE BiOS, 2021, Online Only

Abstract

Newly demonstrated advanced biosensor imaging technologies utilize the unique electromagnetic capabilities of photonic metamaterials to enhance the interaction between light and biological matter. The resulting capabilities address gaps in existing technologies for biomolecular analysis that rely upon enzymatic and chemical amplification, costly instrumentation, and complex assay protocols. Through amplification of the excitation/extraction efficiency of light emitting tags, absorption efficiency of nanoparticle tags, and scattering efficiency of biological analytes, technology platforms have been demonstrated that are capable of ultrasensitive, digital-resolution, room temperature, isothermal, rapid, and highly quantitative biomolecular analysis.

Conference Presentation

Citation Download Citation

Brian T. Cunningham, Taylor D. Canady, Bin Zhao, Shreya Ghosh, Nantao Li, Qinglan Huang, Yanyu Xiong, Glenn Fried, Manish Kohli, Utkan Demirci, and Xing Wang "Photonic metamaterial surfaces for digital resolution biosensor microscopies using enhanced absorption, scattering, and emission", Proc. SPIE 11663, Integrated Sensors for Biological and Neural Sensing, 116630K (5 March 2021); https://doi.org/10.1117/12.2579584

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available