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We propose a Nanodiamond based Biological Physical Unclonable Function for securing in-vivo and in-vitro biosensing devices connected to Internet-of Things healthcare systems for remote patient monitoring . We take advantage of nontoxic biocompatibility and antibacterial activity of nanodiamond films and cavities that can produce strong pseudo-random electromagnetic responses upon electrical or laser triggering due to the fluorescence coming from multiple color centres coupled to such cavities. Such quantum-photonic randomness provides robustness against modelling and side-channel attacks employing machine learning by remote-hackers and can be used to generate a framework of securing biomedical Internet of Things devices and architecture.
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Haimabati Dey, Abhijeet Anand, Peter Bermel, "Securing invasive biomedical sensors in mammalian tissues using nano-diamond-based quantum optical physically unclonable functions," Proc. SPIE 11700, Optical and Quantum Sensing and Precision Metrology, 117003I (5 March 2021); https://doi.org/10.1117/12.2582604