Spectropolarimetry differential diagnosis  of adenocarcinoma and squamous cell cervix carcinoma

Olexander Peresunko; Katerina Chala; Maria Ju. Gruia; Nina Horodynska; Sergey Yermolenko

doi:10.1117/12.2571210

31 December 2020 Spectropolarimetry differential diagnosis of adenocarcinoma and squamous cell cervix carcinoma

Olexander Peresunko, Katerina Chala, Maria Ju. Gruia, Nina Horodynska, Sergey Yermolenko

Proceedings Volume 11718, Advanced Topics in Optoelectronics, Microelectronics and Nanotechnologies X; 117181H (2020) https://doi.org/10.1117/12.2571210
Event: Advanced Topics in Optoelectronics, Microelectronics and Nanotechnologies 2020, 2020, Online Only

Abstract

The aim of this work is to improve the diagnosis of cervical cancer by introducing laser polarimetry and spectropolarization methods of investigation. We have proposed a novel approach for the differentiation of squamous cell carcinoma and cervical adenocarcinoma using laser optics. Obtained by the method of laser polarimetry by Stokes parameter S₄ of native smear with adenocarcinoma of the cervix and squamous cell carcinoma, as well as scraping of the mud canal with endometrial adenocarcinoma and flat cell cancer allows to reliably differentiate the norm from cancer in the native smear and adenocarcinoma from the flat cell cancer in the smear-imprint. The method of spectropolarimetry allows reliably accurately distinguishing the normal epithelium of the cervix from cancer of the cervix, and the parameters of linear dichroism during the spectropolarization study, reliably (р=0,001) differentiate between normal, adenocarcinoma and flat cell cancer of the cervix.

Citation Download Citation

Olexander Peresunko, Katerina Chala, Maria Ju. Gruia, Nina Horodynska, and Sergey Yermolenko "Spectropolarimetry differential diagnosis of adenocarcinoma and squamous cell cervix carcinoma", Proc. SPIE 11718, Advanced Topics in Optoelectronics, Microelectronics and Nanotechnologies X, 117181H (31 December 2020); https://doi.org/10.1117/12.2571210

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