Chemical imaging based on mid-infrared (MIR) spectroscopic contrast is an important technique with a myriad of applications, including biomedical imaging and environmental monitoring. Current MIR cameras, however, lack in performance and are much less affordable compared to mature Si-based devices, which operate in the visible and near-infrared. We demonstrate fast MIR imaging through non-degenerate two-photon absorption (NTA) in a scientific CMOS camera. We show that wide-field MIR images can be obtained at more than 100 frames/s with energies of only a few fJ per pixel. This on-chip approach does not rely on phase-matching, it is alignment-free and it does not necessitate complex post-processing of the images. We show chemically selective MIR imaging of polymers and biological samples, including MIR videos of live organisms and complete 3D volumetric images of objects acquired at rates as fast as 1 volume/s.
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