Holographic optogenetic stimulation with calcium imaging to probe and visualize cardiac activity

Sebastian Junge; Felix Schmieder; Phillip Sasse; Jürgen Czarske; Maria Leilani Torres-Mapa; Alexander Heisterkamp

doi:10.1117/12.2615634

3 December 2021 Holographic optogenetic stimulation with calcium imaging to probe and visualize cardiac activity

Sebastian Junge, Felix Schmieder, Phillip Sasse, Jürgen Czarske, Maria Leilani Torres-Mapa, Alexander Heisterkamp

Proceedings Volume 11921, Emerging Technologies for Cell and Tissue Characterization; 119210G (2021) https://doi.org/10.1117/12.2615634
Event: European Conferences on Biomedical Optics, 2021, Online Only

Abstract

We explore the use of a holographic system using a spatial light modulator combined with calcium imaging to excite ChR2 expressing cardiomyocytes in order to simultaneously probe and visualize the excitability of a cardiac syncytium.

Citation Download Citation

Sebastian Junge, Felix Schmieder, Phillip Sasse, Jürgen Czarske, Maria Leilani Torres-Mapa, and Alexander Heisterkamp "Holographic optogenetic stimulation with calcium imaging to probe and visualize cardiac activity", Proc. SPIE 11921, Emerging Technologies for Cell and Tissue Characterization, 119210G (3 December 2021); https://doi.org/10.1117/12.2615634

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