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We present a needle-injectable wire-free breast lesion localization device that utilizes multi-colored, radio-frequency (RF)-powered LEDs for precise visual guidance during lumpectomy procedures. A red LED provides deep tissue (<10 cm) visible guidance to the lesion, while a green/yellow LED provides more precise close range (<1 cm) visual guidance. The biocompatible device includes an impedance matching circuit and miniature receiver coil optimized for operation in the 6.78 MHz industrial, scientific, and medical RF band. We show that the implant is visible through >5 cm of in vitro and ex vivo breast tissue phantoms using less than 2W of transmitted RF power.
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Sunghoon Rho, Roy A. Stillwell, Patrick Fay, Kandice K. Ludwig, Thomas D. O'Sullivan, "Optically-enhanced wireless breast lesion localization device for use during lumpectomy," Proc. SPIE 11949, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX, 119490F (7 March 2022); https://doi.org/10.1117/12.2606061