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Deep neural networks used for reconstructing sparse-view CT data are typically trained by minimizing a pixel- wise mean-squared error or similar loss function over a set of training images. However, networks trained with such losses are prone to wipe out small, low-contrast features that are critical for screening and diagnosis. To remedy this issue, we introduce a novel training loss inspired by the model observer framework to enhance the detectability of weak signals in the reconstructions. We evaluate our approach on the reconstruction of synthetic sparse-view breast CT data, and demonstrate an improvement in signal detectability with the proposed loss.
Gregory Ongie,Emil Y. Sidky,Ingrid S. Reiser, andXiaochuan Pan
"Optimizing model observer performance in learning-based CT reconstruction", Proc. SPIE 12035, Medical Imaging 2022: Image Perception, Observer Performance, and Technology Assessment, 120350A (4 April 2022); https://doi.org/10.1117/12.2613050
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Gregory Ongie, Emil Y. Sidky, Ingrid S. Reiser, Xiaochuan Pan, "Optimizing model observer performance in learning-based CT reconstruction," Proc. SPIE 12035, Medical Imaging 2022: Image Perception, Observer Performance, and Technology Assessment, 120350A (4 April 2022); https://doi.org/10.1117/12.2613050