Elastographic measurements on tissue phantoms by imaging Rayleigh wave propagation

Amandeep Singh; Renu John

doi:10.1117/12.2648814

28 March 2023 Elastographic measurements on tissue phantoms by imaging Rayleigh wave propagation

Amandeep Singh, Renu John

Proceedings Volume 12381, Optical Elastography and Tissue Biomechanics X; 1238108 (2023) https://doi.org/10.1117/12.2648814
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

The study of variation in biomechanical properties is a significant diagnostic tool for examining malignancy in tissues. Elastography is a potential technique that is used for qualitative and quantitative assessment of abnormal tissues. Optical coherence elastography is a highly efficient and promising technique for inspecting soft biological tissues with microscale resolution. In the present work, we report the elastographic measurement of tissue-mimicking phantoms of varying stiffness using reflection mode holographic imaging. The sinusoidal surface excitation is produced by an electromechanical actuator on the sample over a set of frequencies and the phase map of the surface wave is reconstructed using a phase-shifting algorithm. The preliminary results are well correlated with previously reported literature. The current work has high potential applications for quantifying the biomechanical properties of in-vivo and ex-vivo tissues in clinical practice.

Citation Download Citation

Amandeep Singh and Renu John "Elastographic measurements on tissue phantoms by imaging Rayleigh wave propagation", Proc. SPIE 12381, Optical Elastography and Tissue Biomechanics X, 1238108 (28 March 2023); https://doi.org/10.1117/12.2648814

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