Accurate optical rotation measurement by using spatial polarization modulation and digital image processing

Xueke Wen; Bing Lei; Chao Gao; Fujei Wang

doi:10.1117/12.2652110

20 January 2023 Accurate optical rotation measurement by using spatial polarization modulation and digital image processing

Xueke Wen, Bing Lei, Chao Gao, Fujei Wang

Author Affiliations +

Proceedings Volume 12560, AOPC 2022: Biomedical Optics; 125600C (2023) https://doi.org/10.1117/12.2652110
Event: Applied Optics and Photonics China 2022 (AOPC2022), 2022, Beijing, China

Abstract

Polarimetry is an important noninvasive blood glucose measurement method and attracts extensive attention from researchers. However, one of the difficulties associated with polarimetry is the low concentration of blood glucose, which results in weak optical rotation signals. In this paper, we report a fast and accurate spatial polarization modulation system (SPMS) that can measure the low glucose concentration by analyzing a single digital image. In this system, the rotated polarizer gain mechanism (RPGM) is adopted to amplify the weak optical rotation signals. And in order to extract the optical rotation signals from the background more easily, a vortex phase difference retarder (VPDR) is employed to modulate the optical rotation signals, which is a specially designed birefringent crystal with a vortex phase difference along the azimuth angle. We have established the theoretical model of the SPMS by the Jones matrix theory, and both the simulation experiments with noise and without noise have shown that the SPMS has a resolution of 100mg/dl.

Citation Download Citation

Xueke Wen, Bing Lei, Chao Gao, and Fujei Wang "Accurate optical rotation measurement by using spatial polarization modulation and digital image processing", Proc. SPIE 12560, AOPC 2022: Biomedical Optics, 125600C (20 January 2023); https://doi.org/10.1117/12.2652110

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