iCoagLab permits enhanced anticoagulation management in patients on mechanical circulatory support

Nathaniel Hai; Ziqian Zeng; Eli Foster; Seemantini K. Nadkarni

doi:10.1117/12.3003406

13 March 2024 iCoagLab permits enhanced anticoagulation management in patients on mechanical circulatory support

Nathaniel Hai, Ziqian Zeng, Eli Foster, Seemantini K. Nadkarni

Proceedings Volume 12819, Diagnostic and Therapeutic Applications of Light in Cardiology 2024; 128190I (2024) https://doi.org/10.1117/12.3003406
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Rapidly changing coagulation status is a major challenge in managing and preventing bleeding in patients on mechanical circulatory support. Here, we apply iCoagLab, a hand-held coagulation sensing instrument for timely and comprehensive blood coagulation assessment in patients undergoing cardiac pump implantation. Our results confirm the high accuracy and precision of iCoagLab tests in quantifying key clotting parameters including clotting time, clot stiffness and clotting rate. These studies will help pave the way towards addressing bleeding complications at the point of treatment to potentially manage and prevent hemorrhagic events during mechanical circulatory support.

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Nathaniel Hai, Ziqian Zeng, Eli Foster, and Seemantini K. Nadkarni "iCoagLab permits enhanced anticoagulation management in patients on mechanical circulatory support", Proc. SPIE 12819, Diagnostic and Therapeutic Applications of Light in Cardiology 2024, 128190I (13 March 2024); https://doi.org/10.1117/12.3003406

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KEYWORDS

Blood

Plasma

Biological samples

Laser scattering

Light scattering

Signal intensity

Speckle

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