In-vivo real-time imaging of the human cornea and retina with high-speed line-field optical coherence tomography

Kai Neuhaus; Shuibin Ni; Shanjida Khan; Omkar Tharawe; Siyu Chen; David Huang; Yifan Jian

doi:10.1117/12.3001773

12 March 2024 In-vivo real-time imaging of the human cornea and retina with high-speed line-field optical coherence tomography

Kai Neuhaus, Shuibin Ni, Shanjida Khan, Omkar Tharawe, Siyu Chen, David Huang, Yifan Jian

Author Affiliations +

Proceedings Volume 12824, Ophthalmic Technologies XXXIV; 128240M (2024) https://doi.org/10.1117/12.3001773
Event: SPIE BiOS, 2024, San Francisco, California, United States

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Abstract

A line-field optical coherence tomography (LFOCT) application is implemented for real-time in vivo corneal and retinal imaging. In contrast to other described systems of LFOCT that use single-shot high-speed cameras, we describe the first results utilizing a camera with continuous high-speed data transfer and display. The system is based on a previously published design using a center wavelength of 840nm and a bandwidth of 50nm. The system’s B-frame and en-face display speed reaches up to 5000 frames per second corresponding to 2,500,000 A-lines. A visible light camera is used to detect the interferometric signal to reduce costs and improve optomechanical integration. Balancing the sensitivity vs. acquisition speed allows continuous high data transfer and processing rates and simplifies the implementation as a bedside system. Higher frame rates are important for scan positioning on non-compliant subjects such as infants and children.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

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Kai Neuhaus, Shuibin Ni, Shanjida Khan, Omkar Tharawe, Siyu Chen, David Huang, and Yifan Jian "In-vivo real-time imaging of the human cornea and retina with high-speed line-field optical coherence tomography", Proc. SPIE 12824, Ophthalmic Technologies XXXIV, 128240M (12 March 2024); https://doi.org/10.1117/12.3001773

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