Paper
1 April 2024 Optimal weighting strategies for maximizing contrast-to-noise ratio in photon counting CT images
Yirong Yang, Sen Wang, Grant Stevens, Jiahua Fan, Adam S. Wang
Author Affiliations +
Abstract
Photon counting detectors (PCDs) with energy discrimination capabilities enable spectral imaging and provide higher contrast-to-noise ratio (CNR) than energy integrating detectors (EIDs). Previous work has shown that optimal weighting strategies can further improve CNR. However, a systematic comparison of different weighting strategies and their maximum achievable CNR has not been investigated. In this work, we derive the analytical expressions of the maximum achievable CNR using pre-log optimal weights, post-log optimal weights, and optimal virtual monoenergetic (VM) weights for realistic PCD energy responses and imaging tasks. We compare the CNR performance of these weighting strategies using simulated phantoms and a physical phantom scan for low-contrast tasks. Our results show that for spectral tasks, pre-log optimal weights, post-log optimal weights, and optimal VM weights achieve approximately equal maximum CNR (to within 2% of each other) and outperform total count (TC) images.
(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.
Yirong Yang, Sen Wang, Grant Stevens, Jiahua Fan, and Adam S. Wang "Optimal weighting strategies for maximizing contrast-to-noise ratio in photon counting CT images", Proc. SPIE 12925, Medical Imaging 2024: Physics of Medical Imaging, 1292502 (1 April 2024); https://doi.org/10.1117/12.3006847
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KEYWORDS
Photon counting

Computed tomography

Silicon

Covariance matrices

Calcium

Iodine

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