Non-prewhitening observer applied on grating-based and grating-less phase-contrast imaging: a simulation study

Rickard Brunskog; Michael Bertilson; Olov von Hofsten; Mats Persson

doi:10.1117/12.3005509

1 April 2024 Non-prewhitening observer applied on grating-based and grating-less phase-contrast imaging: a simulation study

Rickard Brunskog, Michael Bertilson, Olov von Hofsten, Mats Persson

Author Affiliations +

Proceedings Volume 12925, Medical Imaging 2024: Physics of Medical Imaging; 129250H (2024) https://doi.org/10.1117/12.3005509
Event: SPIE Medical Imaging, 2024, San Diego, California, United States

Abstract

When implementing differential phase-contrast imaging with current CT detectors the limited pixel size forces one to scan an analyser-grating in front of the detector to resolve the interference pattern. This simulation study compares the approach of using an analyser-grating and the approach of using a high-resolution detector to directly resolve the interference pattern by applying the non-prewhitening observer on dose-matched simulated CT scan reconstructions of the two approaches. A phantom with two concentric cylinders is used and 1000 CT scans are generated with the inner cylinder present and not present. The non-prewhitening observer is applied to the samples and the ROC curve is extracted, together with the results of a 2AFC test, the CNR, and the detectability. The high-resolution approach shows a 20% increase in the phase AUC compared to the grating-based approach, with a similar increase in the 2AFC test score. The image CNR of the phase shows an increase of 134%, with the detectability increasing by 138% when compared to the grating based approach. An ultra-high-resolution detector, capable of directly resolving the interference pattern of differential phase-contrast imaging could change medical imaging CT as we know it. The implementation in a clinical CT would be simpler, could lower cost, and increase the dose-efficiency due to the obviation of the G2-grating, and at the same time provide an additional two diagnostic signals.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Rickard Brunskog, Michael Bertilson, Olov von Hofsten, and Mats Persson "Non-prewhitening observer applied on grating-based and grating-less phase-contrast imaging: a simulation study", Proc. SPIE 12925, Medical Imaging 2024: Physics of Medical Imaging, 129250H (1 April 2024); https://doi.org/10.1117/12.3005509

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