A digital instrument simulator to optimize the development of hyperspectral systems for intraoperative brain mapping

Charly Caredda; Frederic Lange; Luca Giannoni; Ivan Ezhov; Ilias Tachtsidis; Bruno Montcel

doi:10.1117/12.3017488

18 June 2024 A digital instrument simulator to optimize the development of hyperspectral systems for intraoperative brain mapping

Charly Caredda, Frederic Lange, Luca Giannoni, Ivan Ezhov, Ilias Tachtsidis, Bruno Montcel

Author Affiliations +

Proceedings Volume 13010, Tissue Optics and Photonics III; 130100L (2024) https://doi.org/10.1117/12.3017488
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Abstract

Optical imaging is a marker-free, contactless, and non-invasive technique that is able to monitor hemodynamic and metabolic brain response following neuronal activation during neurosurgery. However, a robust quantification is complicated to perform during neurosurgery due to the critical context of the operating room, which makes the calibration and adjustment of optical devices more complex. To overcome this issue, tissue-simulating objects that mimic the properties of biological tissues are required for the development of detection or diagnostic imaging systems. In this study, we developed a digital instrument simulator to optimize the development of a novel hyperspectral system for application in brain/cortex imaging. This digital phantom is based on white Monte Carlo simulations of the light propagation in tissues. The output of the Monte Carlo simulations are integrated with the key instrument parameters in order to produce realistic images. The results can be beneficial and useful within the framework of our EU-funded HyperProbe project, which aims at transforming neuronavigation during glioma resection using novel hyperspectral imaging technology.

Conference Presentation

Citation Download Citation

Charly Caredda, Frederic Lange, Luca Giannoni, Ivan Ezhov, Ilias Tachtsidis, and Bruno Montcel "A digital instrument simulator to optimize the development of hyperspectral systems for intraoperative brain mapping", Proc. SPIE 13010, Tissue Optics and Photonics III, 130100L (18 June 2024); https://doi.org/10.1117/12.3017488

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