Dual-modality high-resolution microendoscope with adjustable maging depth for in vivo cancer detection

Huayu Hou; Alex Kortum; Jennifer Carns; Richard A. Schwarz; Rebecca R. Richards-Kortum

doi:10.1117/12.3034513

21 October 2024 Dual-modality high-resolution microendoscope with adjustable maging depth for in vivo cancer detection

Huayu Hou, Alex Kortum, Jennifer Carns, Richard A. Schwarz, Rebecca R. Richards-Kortum

Author Affiliations +

Proceedings Volume 13186, SPIE Translational Biophotonics + Additive Manufacturing for Photonics 2024; 131860Z (2024) https://doi.org/10.1117/12.3034513
Event: SPIE Translational Biophotonics + Additive Manufacturing for Photonics, 2024, Houston, Texas, United States

Conference Poster

Abstract

We developed a low-cost dual-modality high-resolution microendoscope, which implemented fluorescence imaging and darkfield reflectance imaging to characterize nuclear atypia and dysregulated angiogenesis for in vivo cancer detection. Cell nuclei and microvasculature located at different depths in tissue epithelium were visualized in high spatial resolution by using a compact fiber-based imaging probe with adjustable imaging depth.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

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Huayu Hou, Alex Kortum, Jennifer Carns, Richard A. Schwarz, and Rebecca R. Richards-Kortum "Dual-modality high-resolution microendoscope with adjustable maging depth for in vivo cancer detection", Proc. SPIE 13186, SPIE Translational Biophotonics + Additive Manufacturing for Photonics 2024, 131860Z (21 October 2024); https://doi.org/10.1117/12.3034513

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