Registration of high-resolution images of the retina

Artur V. Cideciyan; Samuel G. Jacobson; Colin M. Kemp; Robert W. Knighton; Joachim H. Nagel

doi:10.1117/12.59439

1 June 1992 Registration of high-resolution images of the retina

Artur V. Cideciyan, Samuel G. Jacobson, Colin M. Kemp, Robert W. Knighton, Joachim H. Nagel

Proceedings Volume 1652, Medical Imaging VI: Image Processing; (1992) https://doi.org/10.1117/12.59439
Event: Medical Imaging VI, 1992, Newport Beach, CA, United States

Abstract

A method of image registration is presented for the case when the deformation between two images can be well approximated with a combination of translation, rotation, and global scaling. The method achieves very high accuracy by combining a global optimization in the 4- dimensional discrete parameter space with a local optimization in the 4-dimensional continuous parameter space. The 4-dimensional global optimization is accomplished with two 2- dimensional optimizations. The Fourier magnitude is used to decouple translation from rotation and scaling, and a log-polar mapping of the Fourier magnitude is used to convert rotation and scaling into shifts. Optimal rotation and scaling parameters are determined with a cross-correlation in the log-polar domain. After compensation for rotation and scaling differences, cross-correlation in the spatial domain yields the translation parameters. The four registration parameters are further refined with a local optimization using the correlation coefficient as a similarity measure in the 4-dimensional continuous parameter space. Results are shown from simulations and from registration of retinal images. For simulated images with a signal-to-noise ratio of -5 dB, the accuracy of the registration method is estimated to be better than 0.07 degrees, 0.1%, and 0.3 pixels for rotation, scaling, and translation, respectively. In the case of 512 X 512 pixel images the computation resource requirements are compatible with high end PCs, i.e., approximately 25 minutes on an Intel 80486/33 MHz based IBM/PC compatible.

Citation Download Citation

Artur V. Cideciyan, Samuel G. Jacobson, Colin M. Kemp, Robert W. Knighton, and Joachim H. Nagel "Registration of high-resolution images of the retina", Proc. SPIE 1652, Medical Imaging VI: Image Processing, (1 June 1992); https://doi.org/10.1117/12.59439

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available