Nd3+ doped glass fluorescent-tip fiber optical probes for quantitative fluence rate dosimetry in biological tissue

Lothar D. Lilge; Glenn N. Merberg; Ralph Sebastian DaCosta; Brian C. Wilson

doi:10.1117/12.180707

28 July 1994 Nd³⁺ doped glass fluorescent-tip fiber optical probes for quantitative fluence rate dosimetry in biological tissue

Lothar D. Lilge, Glenn N. Merberg, Ralph Sebastian DaCosta, Brian C. Wilson

Author Affiliations +

Proceedings Volume 2131, Biomedical Fiber Optic Instrumentation; (1994) https://doi.org/10.1117/12.180707
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

Improved fluorescent-tip fiber optical fluence-rate detectors with solid state fluorophores are presented. In these optical fibers a small end-section of the core is doped with rare earth ions (Nd³⁺, Er³⁺) or is replaced by a fluorescent crystal such as ruby. Thus, this section of the core emits fluorescent light when irradiated with the treatment light to be measured. Angular isotropy and spectral response characteristics of these light detectors are presented. An advantage of solid state probes is their narrow fluorescence emission band and large Stokes shift, allowing also for fluorescence measurements of endogenous or exogenous fluorophores in the tissue. The possibility of simultaneous quantitative fluence-rate and photosensitizer dosimetry by interstitially implanted fiber optic detectors is discussed.

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Lothar D. Lilge, Glenn N. Merberg, Ralph Sebastian DaCosta, and Brian C. Wilson "Nd³⁺ doped glass fluorescent-tip fiber optical probes for quantitative fluence rate dosimetry in biological tissue", Proc. SPIE 2131, Biomedical Fiber Optic Instrumentation, (28 July 1994); https://doi.org/10.1117/12.180707

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