Laser scanning endoscope via an imaging fiber bundle for fluorescence imaging

Lorenz D. Yeboah; Dirk Nestler; Rudolf W. Steiner

doi:10.1117/12.197605

23 December 1994 Laser scanning endoscope via an imaging fiber bundle for fluorescence imaging

Lorenz D. Yeboah, Dirk Nestler, Rudolf W. Steiner

Proceedings Volume 2327, Medical Applications of Lasers II; (1994) https://doi.org/10.1117/12.197605
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

Based on a laser scanning endoscope via an imaging fiber bundle, a new approach for a tumor diagnostic system has been developed to assist physicians in the diagnosis before the actual PDT is carried out. Laser induced, spatially resolved fluorescence images of diseased tissue can be compared with images received by video endoscopy using a white light source. The set- up is required to produce a better contrast between infected and healthy tissue and might serve as a constructive diagnostic help for surgeons. The fundamental idea is to scan a low-power laser beam on an imaging fiber bundle and to achieve a spatially resolved projection on the tissue surface. A sufficiently high laser intensity from the diode laser is concentrated on each single spot of the tissue exciting fluorescence when a dye has previously been accumulated. Subsequently, video image of the tissue is recorded and stored. With an image processing unit, video and fluorescence images are overlaid producing a picture of the fluorescence intensity in the environment of the observed tissue.

Citation Download Citation

Lorenz D. Yeboah, Dirk Nestler, and Rudolf W. Steiner "Laser scanning endoscope via an imaging fiber bundle for fluorescence imaging", Proc. SPIE 2327, Medical Applications of Lasers II, (23 December 1994); https://doi.org/10.1117/12.197605

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