Amorphous silicon area detectors for protein crystallography

Stephan W. Ross; Istvan Naday; Miklos Kanyo; Mary L. Westbrook; Edwin M. Westbrook; Walter Charles Phillips; Martin J. Stanton; Robert A. Street

doi:10.1117/12.206516

10 April 1995 Amorphous silicon area detectors for protein crystallography

Stephan W. Ross, Istvan Naday, Miklos Kanyo, Mary L. Westbrook, Edwin M. Westbrook, Walter Charles Phillips, Martin J. Stanton, Robert A. Street

Author Affiliations +

Proceedings Volume 2415, Charge-Coupled Devices and Solid State Optical Sensors V; (1995) https://doi.org/10.1117/12.206516
Event: IS&T/SPIE's Symposium on Electronic Imaging: Science and Technology, 1995, San Jose, CA, United States

Abstract

Hydrogenated amorphous silicon (a-Si:H) is an electronically readable semiconductor material which can be inexpensively deposited over large surface areas. It is a technology under active development within the Xerox Corporation's Palo Alto Research Center (PARC) for a variety of possible applications. Our calculations indicate that, properly designed and properly applied, this material has great promise as a two-dimensionally sensitive electronic sensor for x-ray area detectors, useful in protein crystallography. The Argonne and Brandeis groups are currently making CCD area detectors, which are excellent but are expensive to build and have a much smaller area then we would like. We therefore have begun to develop large, inexpensive area detectors for protein crystallography, based upon a-Si:H sensors manufactured by Xerox Corporation. Our calculations suggest we can make them large, efficient, fast, high resolution, and with high dynamic range. These detectors should be much less expensive to manufacture than CCD-based detectors, their active areas should be comparable to or larger than image phosphor plate detectors, and they will be electronically readable directly into computer systems with speeds of 1 second or faster.

Citation Download Citation

Stephan W. Ross, Istvan Naday, Miklos Kanyo, Mary L. Westbrook, Edwin M. Westbrook, Walter Charles Phillips, Martin J. Stanton, and Robert A. Street "Amorphous silicon area detectors for protein crystallography", Proc. SPIE 2415, Charge-Coupled Devices and Solid State Optical Sensors V, (10 April 1995); https://doi.org/10.1117/12.206516

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