Light scattering in biological tissues: comparison between theory and experiments of spatial and temporal intensity profiles

Frederic P. Bevilacqua; Pierre Marquet; Christian D. Depeursinge

doi:10.1117/12.228661

18 December 1995 Light scattering in biological tissues: comparison between theory and experiments of spatial and temporal intensity profiles

Frederic P. Bevilacqua, Pierre Marquet, Christian D. Depeursinge

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Proceedings Volume 2626, Photon Propagation in Tissues; (1995) https://doi.org/10.1117/12.228661
Event: BiOS Europe '95, 1995, Barcelona, Spain

Abstract

The propagation of light in biological tissues has been studied theoretically by Monte Carlo simulations and experimentally in vitro on bovine and porcine liver, human breast tissues and fat emulsions. The spatial intensity profile of a scattered collimated beam is measured at the output surface of the sample and compared to theoretical predictions. Measurements on fat emulsions and liver are in good agreement with theory. Absorption and reduced scattering coefficients can be obtained by finding a simulated profile matching our experiments. The precision of these values has been confirmed by the comparison between simulations and experiments on the temporal spread of light pulses. On the contrary the width of the spatial intensity profiles measured on breast tissues are systematically too large to be predicted by our simulations. The heterogeneity of the sample, not considered in simulations, could explain these differences.

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Frederic P. Bevilacqua, Pierre Marquet, and Christian D. Depeursinge "Light scattering in biological tissues: comparison between theory and experiments of spatial and temporal intensity profiles", Proc. SPIE 2626, Photon Propagation in Tissues, (18 December 1995); https://doi.org/10.1117/12.228661

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KEYWORDS

Tissues

Monte Carlo methods

Breast

Liver

Light scattering

Scattering

Charge-coupled devices

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