Signal/background separation by wavelet packets for detection of microcalcifications in mammograms

Hiroyuki Yoshida; Robert M. Nishikawa; Maryellen Lissak Giger; Kunio Doi

doi:10.1117/12.255304

23 October 1996 Signal/background separation by wavelet packets for detection of microcalcifications in mammograms

Hiroyuki Yoshida, Robert M. Nishikawa, Maryellen Lissak Giger, Kunio Doi

Proceedings Volume 2825, Wavelet Applications in Signal and Image Processing IV; (1996) https://doi.org/10.1117/12.255304
Event: SPIE's 1996 International Symposium on Optical Science, Engineering, and Instrumentation, 1996, Denver, CO, United States

Abstract

We developed a method of weighted wavelet packets for separation of small, low contrast signals from large, inhomogeneous background. Our method was applied to the enhancement of microcalcifications on digital mammograms, which appear as small bright spots superimposed on the background representing the structure of breast tissue, for improvement of the performance of our computer-aided diagnosis scheme for detection of clustered microcalcifications. Our method first approximates signals if interest by a set of wavelets that are extracted from a wavelet packet dictionary by means of the matching pursuit algorithm. The selected set of wavelets is then subjected to a supervised learning process for optimization of the weights assigned to individual time-frequency tiles for enhancement of the microcalcifications and suppression of the background structures. In an analysis of 82 regions of interest extracted from our mammographic database, our new method showed a sensitivity of 92 percent and a specificity of 75 percent. Our new method is shown to perform better than our previous method based on the fixed-weight, orthogonal wavelet transform.

Citation Download Citation

Hiroyuki Yoshida, Robert M. Nishikawa, Maryellen Lissak Giger, and Kunio Doi "Signal/background separation by wavelet packets for detection of microcalcifications in mammograms", Proc. SPIE 2825, Wavelet Applications in Signal and Image Processing IV, (23 October 1996); https://doi.org/10.1117/12.255304

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