Portable flow immunosensor for detecting drugs and explosives

Anne W. Kusterbeck; Paul R. Gauger; Paul T. Charles

doi:10.1117/12.266773

17 February 1997 Portable flow immunosensor for detecting drugs and explosives

Anne W. Kusterbeck, Paul R. Gauger, Paul T. Charles

Proceedings Volume 2937, Chemistry- and Biology-Based Technologies for Contraband Detection; (1997) https://doi.org/10.1117/12.266773
Event: Enabling Technologies for Law Enforcement and Security, 1996, Boston, MA, United States

Abstract

To assist in airport surveillance efforts, a biosensor based on antibody recognition of individual explosives and drugs has been developed at the Naval Research Laboratory. Analysis of samples containing ng/mL levels of the material are completed in under one minute. Immunoassays for the explosives and the five major drugs of abuse are currently available. The intrinsic nature of antigen-antibody binding also provides the unit with an inherently high degree of selectivity. A portable version of the biosensor that can be run by non-technical personnel is also being engineered. The device, including pumps and fluorometer, will be housed on a modified PCMCIA cartridge fitted into a laptop computer. To run assays, a disposable coupon containing the antibody/fluorescent-antigen complex is inserted into the unit and samples are introduced via a sampling port. Results can be viewed in real time or stored on the computer for later data retrieval and analysis.

Citation Download Citation

Anne W. Kusterbeck, Paul R. Gauger, and Paul T. Charles "Portable flow immunosensor for detecting drugs and explosives", Proc. SPIE 2937, Chemistry- and Biology-Based Technologies for Contraband Detection, (17 February 1997); https://doi.org/10.1117/12.266773

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