Bladder welding in rats using a controlled-temperature CO2 laser system

Leonid Lobik; Avi Ravid; Israel Nissencorn; Noam Kariv; J. Bernheim; Abraham Katzir

doi:10.1117/12.312323

1 July 1998 Bladder welding in rats using a controlled-temperature CO₂ laser system

Leonid Lobik, Avi Ravid, Israel Nissencorn, Noam Kariv, J. Bernheim, Abraham Katzir

Proceedings Volume 3245, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII; (1998) https://doi.org/10.1117/12.312323
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States

Abstract

The promising clinical potential for laser welding of tissues has generated a growing interest in this field. As improved laser welding system was constructed in this work. It was based on IR transmitting AgClBr fibers for laser power delivery and for temperature control. The fiberoptic system was used to transmit CO₂ laser power for tissue heating and for non contact (radiometric) temperature monitoring and control. Bladder opening (cystotomy) was performed in 38 rats and 33 of the animals underwent laser welding. In 5 rats (control group) the bladder wound was closed with one layer continuous 6-0 dexon sutures. The rats were sacrificed on days 2, 10 and 30 for histological study. The temperature control of the upper tissue surface was set at 70 plus or minus 5 degrees Celsius. Bladder closure using laser welding was successful in 31/33 (94%) of the animals. The quality of the weld was examined immediately after the operation, revealing a water tight closure of the bladder wall. The histological examination showed an excellent welding and healing of the tissue. These results demonstrate the potential of temperature controlled CO₂ laser welding.

Citation Download Citation

Leonid Lobik, Avi Ravid, Israel Nissencorn, Noam Kariv, J. Bernheim, and Abraham Katzir "Bladder welding in rats using a controlled-temperature CO₂ laser system", Proc. SPIE 3245, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII, (1 July 1998); https://doi.org/10.1117/12.312323

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