Coherent signal analysis in color Doppler optical coherence tomography

Manish D. Kulkarni; Ton G. J. M. van Leeuwen; Siavash Yazdanfar; Joseph A. Izatt

doi:10.1117/12.306072

24 April 1998 Coherent signal analysis in color Doppler optical coherence tomography

Manish D. Kulkarni, Ton G. J. M. van Leeuwen, Siavash Yazdanfar, Joseph A. Izatt

Proceedings Volume 3251, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications II; (1998) https://doi.org/10.1117/12.306072
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States

Abstract

Color Doppler optical coherence tomography (CDOCT) is a recent innovation which allows spatially localized flow velocity mapping simultaneous with micro-structural imaging. We present a theoretical model for velocity image formation in CDOCT. The equivalence between the heterodyne detector current power spectrum in CDOCT and the optical source power spectrum is established. We show that stochastic modifications of the detected electronic spectrum by fluctuating scatterer distributions in the flow field give rise to unavoidable velocity estimation inaccuracies, as well as to the fundamental trade-off between the maximum velocity image acquisition rate and the estimated velocity precision. Novel algorithms which permit high fidelity depth-resolved measurements of velocities in turbid media with optimal frame rate are also reported.

Citation Download Citation

Manish D. Kulkarni, Ton G. J. M. van Leeuwen, Siavash Yazdanfar, and Joseph A. Izatt "Coherent signal analysis in color Doppler optical coherence tomography", Proc. SPIE 3251, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications II, (24 April 1998); https://doi.org/10.1117/12.306072

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