Osmotical liquid diffusion within sclera

Alexey N. Bashkatov; Elina A. Genina; Vyacheslav I. Kochubey; Nina A. Lakodina; Valery V. Tuchin

doi:10.1117/12.387539

7 June 2000 Osmotical liquid diffusion within sclera

Alexey N. Bashkatov, Elina A. Genina, Vyacheslav I. Kochubey, Nina A. Lakodina, Valery V. Tuchin

Proceedings Volume 3908, Ophthalmic Technologies X; (2000) https://doi.org/10.1117/12.387539
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

We present experimental results of investigation of the optical properties of the human eye sclera controlled by administration of osmotically active chemical, such as glucose solution with various concentrations. Administration of chemical agent induces diffusion of matter and as a result equalization of the refractive indices of collagen and ground material. Results of experimental study of influence of osmotical liquid (glucose solution) on reflectance and transmittance spectra of human sclera are presented. In vitro reflectance and transmittance spectra of the human sclera samples were investigated by commercially available spectrophotometer CARY-2415. The significant increasing of the transmittance and decreasing of the reflectance of human sclera samples under action of osmotical solutions were demonstrated. Results of our study show that the degree of the sclera samples clearing is increased with increasing of the chemical agent concentration in solution. The diffusion coefficients of glucose solution with various concentrations within scleral tissue was estimated.

Citation Download Citation

Alexey N. Bashkatov, Elina A. Genina, Vyacheslav I. Kochubey, Nina A. Lakodina, and Valery V. Tuchin "Osmotical liquid diffusion within sclera", Proc. SPIE 3908, Ophthalmic Technologies X, (7 June 2000); https://doi.org/10.1117/12.387539

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