Imaging with dual-interfering sources

Xavier Intes; Vasilis Ntziachristos; Arjun G. Yodh; Britton Chance

doi:10.1117/12.434471

29 June 2001 Imaging with dual-interfering sources

Xavier Intes, Vasilis Ntziachristos, Arjun G. Yodh, Britton Chance

Proceedings Volume 4250, Optical Tomography and Spectroscopy of Tissue IV; (2001) https://doi.org/10.1117/12.434471
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

Dual interfering source systems have been shown to be more sensitive to the presence of absorbing inhomogeneities than single-source systems. They are used to localize accurately deep inhomogeneities with backprojection methods. However, there is not actually a method to perform indirect imaging with such techniques. In this work, a tomographic reconstruction method for an absorbing perturbation in highly scattering media and for phased array system is derived. The perturbation approach to solve the heterogeneous diffusion equation is used with the first order Rytov expansion. Analytical weight functions necessary to solve the inverse problem are obtained. Validity of the derived analytical expressions was checked with reconstructions from simulated data obtained with finite difference solutions of the diffusion equation and for a media mimicking breast tissue.

Citation Download Citation

Xavier Intes, Vasilis Ntziachristos, Arjun G. Yodh, and Britton Chance "Imaging with dual-interfering sources", Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); https://doi.org/10.1117/12.434471

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